21: Two One
Sega Dreamcast · 2001
About this game
21: Two One is a visual novel adventure game originally released for PC with adult content which is then ported to Dreamcast.
Story After losing you mother to an illness, one day you decided to become a doctor and give your best to help other people not go through the same pain and ordeal.
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Your name is Takuya Kirishima, and you lived up to your expectations and became a skilled surgeon who can perform any surgery without a problem.
But patients still die, and you may not be able to save them all... that brings the lack of confidence in you as a doctor and makes you question your goal to become a doctor.
Seri Sakaki is a young nurse, and an old childhood friend of yours who is trying to help you deal with your limitations as a human.
At such time, a murder occurs at the hospital and people start suffering from an unknown strange disease.
The police investigation into it has been launched which yields many suspects and mysteries, and even more questions.
Gameplay At its core, this is a visual novel adventure which determines the course of the story based on the choices you make.
However, you can also set the mood of your character to trusting, normal, or suspicious, which will also affect the course of the game (quite similar to how it was done in Blade Runner ).
You will also be able to check the human relation chart to see connection between characters, as well as flow chart to see how the game story branched.
About Sega Dreamcast
Sega's final console, the Dreamcast (1998/1999), was ahead of its time with built-in internet connectivity and an influential library, but a short commercial lifespan cut its game catalog short. That abrupt end means Dreamcast print runs were smaller across the board than a longer-lived console would have had, and it's now one of the more actively collected fifth/sixth-generation systems specifically because of that scarcity.
Gamevaro tracks 21: Two One for Sega Dreamcast with separate market values for loose, complete-in-box (CIB) and factory-sealed copies, sourced from real eBay sales. Prices also vary by region — PAL, NTSC-U and NTSC-J releases of the same game often sell for different amounts due to print run sizes and regional collector demand.
Adding 21: Two One to a Gamevaro collection takes seconds — search by title or scan the box barcode, and the app fills in cover art, release details and current pricing automatically. This DC release dates back to 2001.
Price history
Market values by condition
NTSC-J
Recent sales
| Date | Type | Region | Price |
|---|---|---|---|
| 2026-07-14 | Item only | NTSC-J | €31.49 |
| 2026-07-12 | Manual Only | NTSC-J | €5.25 |
| 2026-07-12 | Item only | NTSC-J | €6.51 |
| 2026-07-12 | Complete in Box | NTSC-J | €21.00 |
| 2026-07-12 | New (sealed) | NTSC-J | €26.36 |
| 2026-07-12 | Graded New | NTSC-J | €28.99 |
| 2026-07-12 | Box Only | NTSC-J | €8.40 |
| 2026-07-10 | Graded New | NTSC-J | €28.98 |
| 2026-07-10 | Box Only | NTSC-J | €8.40 |
| 2026-07-10 | New (sealed) | NTSC-J | €26.35 |
| 2026-07-10 | Manual Only | NTSC-J | €5.25 |
| 2026-07-10 | Item only | NTSC-J | €6.51 |
| 2026-07-10 | Complete in Box | NTSC-J | €20.99 |
| 2026-06-18 | Graded New | NTSC-J | €28.58 |
| 2026-06-18 | Manual Only | NTSC-J | €5.18 |
| 2026-06-18 | Box Only | NTSC-J | €8.28 |
| 2026-06-18 | Item only | NTSC-J | €6.42 |
| 2026-06-18 | New (sealed) | NTSC-J | €25.99 |
| 2026-06-18 | Complete in Box | NTSC-J | €20.70 |
| 2026-06-08 | Complete in Box | NTSC-J | €20.62 |
| 2026-06-08 | Manual Only | NTSC-J | €5.15 |
| 2026-06-08 | New (sealed) | NTSC-J | €25.88 |
| 2026-06-08 | Graded New | NTSC-J | €28.47 |
| 2026-06-08 | Box Only | NTSC-J | €8.25 |
| 2026-06-08 | Item only | NTSC-J | €6.39 |
| 2026-05-17 | Item only | NTSC-J | €6.37 |
| 2026-05-17 | Graded New | NTSC-J | €28.36 |
| 2026-05-17 | New (sealed) | NTSC-J | €25.78 |
| 2026-05-17 | Manual Only | NTSC-J | €5.13 |
| 2026-05-17 | Complete in Box | NTSC-J | €20.54 |
Market insights
Rarity & condition
21: Two One has a steady sales history on the tracked marketplaces, meaning enough copies circulate to establish a reliable market price.
Complete-in-box (CIB) copies typically command a premium over loose cartridges/discs because the original box and manual are more fragile and get discarded or damaged over time — fewer complete sets survive.
Frequently asked questions
How much is 21: Two One worth?
21: Two One for Sega Dreamcast is currently worth €31.49 loose, €21.00 complete in box, and €26.36 factory sealed. Prices are based on real sales and update regularly on Gamevaro.
Is 21: Two One rare?
21: Two One has a steady sales history on the tracked marketplaces, meaning it trades hands regularly and isn't considered particularly rare.
What's the difference between loose, CIB and sealed for 21: Two One?
Loose means cartridge or disc only, CIB (complete in box) includes the original box and manual, and sealed means factory-sealed and never opened. For 21: Two One, loose is €31.49 and CIB is €21.00 — CIB commands a premium because original boxes and manuals are fragile and often don't survive.
Ratings & Reviews
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