Destroy All Humans!
Nintendo Wii · 2005
About this game
Crypto is back yet again for the third game in the series.
The game takes place sometime in the 1970s, a decade after the last installment.
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Crypto and his mentor Orthopox attempt to exploit the popularity of Big Willy, a fast food restaurant owned by Pox.
His secret recipe is actually human meat, served from the dead bodies that were left behind after Crypto got their brain stems.
A kidnapped heiress by the name of Patty Wurst has discovered the secret recipe of the restaurant, and Crypto and Pox set on an adventure to stop her before she can expose them.
The game is set in the 1970s.
There is now a third way to unleash fury besides on foot and in a UFO aircraft: a Big Willy Machine! There are five different places to explore: Harbor City, Fairfield, Vietmahl, Fantasy Island, and Antarctica.
There are futuristic weapons and unique mental abilities.
It wouldn't be a Destroy all Humans! game without humor and over the top, non-stop action.
Popular abilities such as Psychokinesis and Body Snatch return as well as Crypto's Zap-O-Matic and Disintegrator Ray.
New abilites include the saucer's Electro-Cone and Quantum Deconstructor.
Crypto also has new guns, including the Ball Lightning and a zombie gun that turns its victims into zombies.
About Nintendo Wii
Launched in 2006, the Wii's motion controls (Wii Remote) brought casual and non-traditional players into console gaming at a scale no prior system had achieved, making it one of the best-selling consoles ever. Because so many Wii units sold with bundled software like Wii Sports, the bulk of the library is inexpensive to collect — but it also means truly rare Wii titles (often niche Japanese-only releases) stand out sharply from the norm.
Gamevaro tracks Destroy All Humans! for Nintendo Wii with separate market values for loose, complete-in-box (CIB) and factory-sealed copies, sourced from real eBay sales. Prices also vary by region — PAL, NTSC-U and NTSC-J releases of the same game often sell for different amounts due to print run sizes and regional collector demand.
Adding Destroy All Humans! to a Gamevaro collection takes seconds — search by title or scan the box barcode, and the app fills in cover art, release details and current pricing automatically. This WII release dates back to 2005.
Market values by condition
PAL
Recent sales
| Date | Type | Region | Price |
|---|---|---|---|
| 2026-07-12 | Boxed (CIB) | NTSC-J | €9.62 |
| 2026-07-12 | Loose / Item only | NTSC-J | €8.23 |
| 2026-07-12 | Sealed / New | NTSC-J | €22.74 |
| 2026-07-11 | Sealed / New | NTSC-U | €22.74 |
| 2026-07-11 | Boxed (CIB) | NTSC-U | €9.62 |
| 2026-07-11 | Loose / Item only | NTSC-U | €8.29 |
| 2026-07-11 | Loose / Item only | PAL | €9.97 |
Market insights
Rarity & condition
Only a handful of market sales have been tracked for Destroy All Humans!, suggesting it doesn't trade hands very often — a sign of relative scarcity compared to more common Nintendo Wii titles.
Complete-in-box (CIB) copies typically command a premium over loose cartridges/discs because the original box and manual are more fragile and get discarded or damaged over time — fewer complete sets survive.
Frequently asked questions
How much is Destroy All Humans! worth?
Destroy All Humans! for Nintendo Wii is currently worth €9.97 loose. Prices are based on real sales and update regularly on Gamevaro.
Is Destroy All Humans! rare?
Destroy All Humans! has only a handful of tracked market sales, suggesting relative scarcity compared to more common Nintendo Wii titles.
What's the difference between loose, CIB and sealed for Destroy All Humans!?
Loose means cartridge or disc only, CIB (complete in box) includes the original box and manual, and sealed means factory-sealed and never opened. These are tracked as separate market values because the price gap between them can be significant, especially for older releases.
Is Destroy All Humans! worth more in PAL or NTSC?
The PAL version of Destroy All Humans! is currently worth €9.97 loose, versus €8.29 for NTSC-U. Regional price differences usually come down to print run size and regional collector demand.
Ratings & Reviews
Also on other platforms
More Nintendo Wii games