Alien Syndrome
Nintendo Wii · 2007
About this game
Alien Syndrome is a top down shooter inspired by SEGA 's original Alien Syndrome action game.
The games story takes place thousands of years in the future; by this point in time mankind has explored many parts of the galaxy and established numerous colonies.
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One such colony, Seti-Alpha 5 (SAT5), has ceased communications for some reason and it is your job to head to SAT5 and investigate what went wrong.
Upon arrival, you encounter the alien syndrome, a force which can mutate man and machine into deadly aliens.
These events take place roughly 100 years after those in the original Alien Syndrome .
When you begin the game you can select one of several characters as well as choose a character specialty (such as demolitions expert, firebug, seal, tank, and sharpshooter).
The specialty you select will determine your initial character stats; as you play through the game you earn levels which provide you points to allocate towards improving your stats.
The character stats help determine your characters accuracy in ranged or close attacks, speed, healing power, resistance to fire/radiation, armor strength, and so on.
Similar to the original game, the action is viewed top down.
You'll need to explore the numerous corridors and rooms found on SAT5 and eliminate the numerous alien invaders found there.
Mission objectives are often provided to you which need to be completed.
Additional weapons, ammo, and other useful items can be found throughout the levels.
Your character has a limited amount of energy, and if all energy is lost then you will need to begin again at the last checkpoint crossed.
About Nintendo Wii
Launched in 2006, the Wii's motion controls (Wii Remote) brought casual and non-traditional players into console gaming at a scale no prior system had achieved, making it one of the best-selling consoles ever. Because so many Wii units sold with bundled software like Wii Sports, the bulk of the library is inexpensive to collect — but it also means truly rare Wii titles (often niche Japanese-only releases) stand out sharply from the norm.
Gamevaro tracks Alien Syndrome for Nintendo Wii with separate market values for loose, complete-in-box (CIB) and factory-sealed copies, sourced from real eBay sales. Prices also vary by region — PAL, NTSC-U and NTSC-J releases of the same game often sell for different amounts due to print run sizes and regional collector demand.
Adding Alien Syndrome to a Gamevaro collection takes seconds — search by title or scan the box barcode, and the app fills in cover art, release details and current pricing automatically. This WII release dates back to 2007.
Price history
Market values by condition
PAL
NTSC-U
Recent sales
| Date | Type | Region | Price |
|---|---|---|---|
| 2026-07-12 | Item only | NTSC-U | €4.12 |
| 2026-07-12 | Box Only | NTSC-U | €2.01 |
| 2026-07-12 | Complete in Box | NTSC-U | €5.09 |
| 2026-07-12 | Manual Only | NTSC-U | €1.26 |
| 2026-07-12 | Box Only | PAL | €2.08 |
| 2026-07-12 | Item only | NTSC-U | €8.74 |
| 2026-07-12 | Complete in Box | PAL | €5.21 |
| 2026-07-12 | Item only | PAL | €4.58 |
| 2026-07-12 | New (sealed) | NTSC-U | €20.30 |
| 2026-07-12 | Graded New | NTSC-U | €16.89 |
| 2026-07-12 | Graded New | PAL | €18.78 |
| 2026-07-12 | New (sealed) | NTSC-U | €15.35 |
| 2026-07-12 | Complete in Box | NTSC-U | €9.88 |
| 2026-07-12 | Manual Only | PAL | €1.30 |
| 2026-07-12 | New (sealed) | PAL | €17.07 |
| 2026-07-11 | Item only | PAL | €11.35 |
| 2026-07-11 | New (sealed) | PAL | €24.59 |
| 2026-07-10 | New (sealed) | PAL | €17.06 |
| 2026-07-10 | Manual Only | NTSC-U | €1.37 |
| 2026-07-10 | Complete in Box | PAL | €5.21 |
| 2026-07-10 | Item only | NTSC-U | €4.12 |
| 2026-07-10 | Box Only | NTSC-U | €2.20 |
| 2026-07-10 | Item only | PAL | €4.57 |
| 2026-07-10 | New (sealed) | NTSC-U | €15.35 |
| 2026-07-10 | Manual Only | PAL | €1.30 |
| 2026-07-10 | Graded New | PAL | €18.77 |
| 2026-07-10 | Box Only | PAL | €2.08 |
| 2026-07-10 | Complete in Box | NTSC-U | €5.03 |
| 2026-07-10 | Graded New | NTSC-U | €16.89 |
| 2026-06-18 | Graded New | PAL | €18.51 |
Market insights
Rarity & condition
Alien Syndrome has a steady sales history on the tracked marketplaces, meaning enough copies circulate to establish a reliable market price.
Complete-in-box (CIB) copies typically command a premium over loose cartridges/discs because the original box and manual are more fragile and get discarded or damaged over time — fewer complete sets survive.
Frequently asked questions
How much is Alien Syndrome worth?
Alien Syndrome for Nintendo Wii is currently worth €11.35 loose, €5.21 complete in box, and €17.07 factory sealed. Prices are based on real sales and update regularly on Gamevaro.
Is Alien Syndrome rare?
Alien Syndrome has a steady sales history on the tracked marketplaces, meaning it trades hands regularly and isn't considered particularly rare.
What's the difference between loose, CIB and sealed for Alien Syndrome?
Loose means cartridge or disc only, CIB (complete in box) includes the original box and manual, and sealed means factory-sealed and never opened. For Alien Syndrome, loose is €11.35 and CIB is €5.21 — CIB commands a premium because original boxes and manuals are fragile and often don't survive.
Is Alien Syndrome worth more in PAL or NTSC?
The PAL version of Alien Syndrome is currently worth €11.35 loose, versus €8.74 for NTSC-U. Regional price differences usually come down to print run size and regional collector demand.
Ratings & Reviews
Also on other platforms
More Nintendo Wii games